Functional Evaluation of Prolactin Secretion: a Guide to Therapy

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Abstract

Stimulation and inhibition tests are proposed for evaluating prolactin secretion. Thyrotropin-releasing hormone (TRH) stimulates the release of prolactin from the pituitary. Chlorpromazine acts presumably at the hypothalamic level to increase prolactin secretion. L-Dopa (D,L-α-hydrazino-α-methyl-β-[3,4-di-hydroxyphenyl]) has the opposite effect; it inhibits prolactin secretion and may be effective in suppressing galactorrhea.

Authors

H. Friesen, H. Guyda, P. Hwang, J. E. Tyson, A. Barbeau