Deposition and clearance of 2 μ particles in the tracheobronchial tree of normal subjects—smokers and nonsmokers

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Abstract

Deposition and clearance of inhaled particles of iron oxide labeled with 198Au were studied in 19 normal subjects (10 nonsmokers and 9 smokers). For this purpose, monodisperse aerosols of particles with a 2 μ diameter were produced in a spinning disc atomizer. Thoracic counts and images with a scintillation camera were begun immediately after inhalation of the aerosol and continued for 6 hr.

Authors

Ruy V. Lourenço, Mary F. Klimek, Claudia J. Borowski