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Research Article Free access | 10.1172/JCI105938

Increased urinary excretion of acidic mucopolysaccharides in exophthalmos

Roger J. Winand

1National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland 20014

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Published December 1, 1968 - More info

Published in Volume 47, Issue 12 on December 1, 1968
J Clin Invest. 1968;47(12):2563–2568. https://doi.org/10.1172/JCI105938.
© 1968 The American Society for Clinical Investigation
Published December 1, 1968 - Version history
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Abstract

The excretion of mucopolysaccharides normally found in urine (chondroitin, chondroitin sulfates A and C, keratosulfate, and heparitin sulfate) is increased approximately twofold in patients with progresive exophthalmos. A threefold elevation of total serum mucopolysaccharides is also found. These increases are unrelated to thyroid function.

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