The Steroid Content of Adrenal Adenomas and Measurements of Aldosterone Production in Patients with Essential Hypertension and Primary Aldosteronism

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Abstract

The content of aldosterone, corticosterone, and cortisol has been assayed in normal adrenal tissue obtained at autopsy and in adrenal adenomas from both normotensive and hypertensive patients obtained at autopsy and from patients with primary aldosteronism obtained at surgery. The content of aldosterone and corticosterone in the adenomas of patients with essential hypertension was similar to that of normal adrenal tissue and much less than that of adenomas from patients with primary aldosteronism.

Authors

Norman M. Kaplan