Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI105173

Studies of Experimental Renal Failure in Dogs. I. Effect of 5/6 Nephrectomy on Concentrating and Diluting Capacity of Residual Nephrons

Jack W. Coburn, Harvey C. Gonick, Milton E. Rubini, and Charles R. Kleeman

Medical Service, Wadsworth Hospital, Veterans Administration Center, Los Angeles, Calif.

Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, Calif.

Department of Medicine, Mount Sinai Hospital, Los Angeles, Calif.

†

Work performed in part during tenure of U. S. Public Health Service postdoctoral research fellowship of the National Institute of Arthritis and Metabolic Diseases. Present address: Department of Metabolism, Walter Reed Army Institute of Research, Washington, D. C.

‡

Address requests for reprints to: Dr. Charles R. Kleeman, Mount Sinai Hospital, 8720 Beverly Boulevard, Los Angeles 48, Calif.

*

Submitted for publication June 4, 1964; accepted December 14, 1964.

Supported in part by U. S. Public Health Service grants (AM 01634-06 and APD 13952) and a Los Angeles County Heart Association grant (318).

Presented in part before the Sixteenth Annual Meeting of the Western Society for Clinical Research, February 1, 1963, Carmel, Calif.

Find articles by Coburn, J. in: PubMed | Google Scholar

Medical Service, Wadsworth Hospital, Veterans Administration Center, Los Angeles, Calif.

Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, Calif.

Department of Medicine, Mount Sinai Hospital, Los Angeles, Calif.

†

Work performed in part during tenure of U. S. Public Health Service postdoctoral research fellowship of the National Institute of Arthritis and Metabolic Diseases. Present address: Department of Metabolism, Walter Reed Army Institute of Research, Washington, D. C.

‡

Address requests for reprints to: Dr. Charles R. Kleeman, Mount Sinai Hospital, 8720 Beverly Boulevard, Los Angeles 48, Calif.

*

Submitted for publication June 4, 1964; accepted December 14, 1964.

Supported in part by U. S. Public Health Service grants (AM 01634-06 and APD 13952) and a Los Angeles County Heart Association grant (318).

Presented in part before the Sixteenth Annual Meeting of the Western Society for Clinical Research, February 1, 1963, Carmel, Calif.

Find articles by Gonick, H. in: PubMed | Google Scholar

Medical Service, Wadsworth Hospital, Veterans Administration Center, Los Angeles, Calif.

Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, Calif.

Department of Medicine, Mount Sinai Hospital, Los Angeles, Calif.

†

Work performed in part during tenure of U. S. Public Health Service postdoctoral research fellowship of the National Institute of Arthritis and Metabolic Diseases. Present address: Department of Metabolism, Walter Reed Army Institute of Research, Washington, D. C.

‡

Address requests for reprints to: Dr. Charles R. Kleeman, Mount Sinai Hospital, 8720 Beverly Boulevard, Los Angeles 48, Calif.

*

Submitted for publication June 4, 1964; accepted December 14, 1964.

Supported in part by U. S. Public Health Service grants (AM 01634-06 and APD 13952) and a Los Angeles County Heart Association grant (318).

Presented in part before the Sixteenth Annual Meeting of the Western Society for Clinical Research, February 1, 1963, Carmel, Calif.

Find articles by Rubini, M. in: PubMed | Google Scholar

Medical Service, Wadsworth Hospital, Veterans Administration Center, Los Angeles, Calif.

Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, Calif.

Department of Medicine, Mount Sinai Hospital, Los Angeles, Calif.

†

Work performed in part during tenure of U. S. Public Health Service postdoctoral research fellowship of the National Institute of Arthritis and Metabolic Diseases. Present address: Department of Metabolism, Walter Reed Army Institute of Research, Washington, D. C.

‡

Address requests for reprints to: Dr. Charles R. Kleeman, Mount Sinai Hospital, 8720 Beverly Boulevard, Los Angeles 48, Calif.

*

Submitted for publication June 4, 1964; accepted December 14, 1964.

Supported in part by U. S. Public Health Service grants (AM 01634-06 and APD 13952) and a Los Angeles County Heart Association grant (318).

Presented in part before the Sixteenth Annual Meeting of the Western Society for Clinical Research, February 1, 1963, Carmel, Calif.

Find articles by Kleeman, C. in: PubMed | Google Scholar

Published April 1, 1965 - More info

Published in Volume 44, Issue 4 on April 1, 1965
J Clin Invest. 1965;44(4):603–614. https://doi.org/10.1172/JCI105173.
© 1965 The American Society for Clinical Investigation
Published April 1, 1965 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 603
page 603
icon of scanned page 604
page 604
icon of scanned page 605
page 605
icon of scanned page 606
page 606
icon of scanned page 607
page 607
icon of scanned page 608
page 608
icon of scanned page 609
page 609
icon of scanned page 610
page 610
icon of scanned page 611
page 611
icon of scanned page 612
page 612
icon of scanned page 613
page 613
icon of scanned page 614
page 614
Version history
  • Version 1 (April 1, 1965): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts