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Research Article Free access | 10.1172/JCI104065

THE PHYSIOLOGICAL SIGNIFICANCE OF THE SECRETION OF ENDOGENOUS INSULIN INTO THE PORTAL CIRCULATION. III. EVIDENCE FOR A DIRECT IMMEDIATE EFFECT OF INSULIN ON THE BALANCE OF GLUCOSE ACROSS THE LIVER

Leonard L. Madison, Burton Combes, Reuben Adams, and William Strickland

Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas, Texas

Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas

‡

Established Investigator of The American Heart Association.

*

This work was supported in part by a grant from the Upjohn Company and in part by the Dallas Heart Association.

†

Presented in part before the Metabolism Section of the American Society for Clinical Investigation, Atlantic City, May 3, 1959, and at the Symposium on Insulin and Oral Hypoglycemic Agents held at the Indiana University Medical Center, Indianapolis, February 27 and 28, 1959.

Find articles by Madison, L. in: JCI | PubMed | Google Scholar

Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas, Texas

Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas

‡

Established Investigator of The American Heart Association.

*

This work was supported in part by a grant from the Upjohn Company and in part by the Dallas Heart Association.

†

Presented in part before the Metabolism Section of the American Society for Clinical Investigation, Atlantic City, May 3, 1959, and at the Symposium on Insulin and Oral Hypoglycemic Agents held at the Indiana University Medical Center, Indianapolis, February 27 and 28, 1959.

Find articles by Combes, B. in: JCI | PubMed | Google Scholar

Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas, Texas

Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas

‡

Established Investigator of The American Heart Association.

*

This work was supported in part by a grant from the Upjohn Company and in part by the Dallas Heart Association.

†

Presented in part before the Metabolism Section of the American Society for Clinical Investigation, Atlantic City, May 3, 1959, and at the Symposium on Insulin and Oral Hypoglycemic Agents held at the Indiana University Medical Center, Indianapolis, February 27 and 28, 1959.

Find articles by Adams, R. in: JCI | PubMed | Google Scholar

Department of Internal Medicine, University of Texas Southwestern Medical School, Dallas, Texas

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School, Dallas, Texas

Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas

‡

Established Investigator of The American Heart Association.

*

This work was supported in part by a grant from the Upjohn Company and in part by the Dallas Heart Association.

†

Presented in part before the Metabolism Section of the American Society for Clinical Investigation, Atlantic City, May 3, 1959, and at the Symposium on Insulin and Oral Hypoglycemic Agents held at the Indiana University Medical Center, Indianapolis, February 27 and 28, 1959.

Find articles by Strickland, W. in: JCI | PubMed | Google Scholar

Published March 1, 1960 - More info

Published in Volume 39, Issue 3 on March 1, 1960
J Clin Invest. 1960;39(3):507–522. https://doi.org/10.1172/JCI104065.
© 1960 The American Society for Clinical Investigation
Published March 1, 1960 - Version history
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