Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Pancreatic Cancer (Jul 2025)
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Top
  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal
  • Top
  • Version history
  • Article usage
  • Citations to this article

Advertisement

Research Article Free access | 10.1172/JCI101787

THE METABOLIC EFFECTS OF STEROID HORMONES IN OSTEOPOROSIS

Edward C. Reifenstein Jr. and Fuller Albright

Medical Service of the Massachusetts General Hospital and the Department of Medicine of the Harvard Medical School, Boston

1

The expense of these studies was defrayed by grants from the Josiah Macy, Jr. Foundation, from the Rockefeller Foundation, and from the National Research Council (Committee for Research in the Problems of Sex). A bed supported by the Mallinckrodt Chemical Company on the Metabolic Ward was used for part of these studies.

2

Presented in part at the twenty-sixth annual meeting of the Association for the Study of Internal Secretions, Atlantic City, New Jersey, June 8, 1942, in connection with a symposium on “Relation of Endocrines to Skeletal Development”; an outline of this presentation may be found in: Reifenstein, E. C., Jr.; Albright, F.; Parson, W.; and Bloomberg, E.: The effect of estradiol benzoate and of testosterone propionate and of combinations of both on post-menopausal osteoporosis and senile osteoporosis, Endocrinology, 30: S1024 (1942). Also presented in part at the first annual meeting of the American Federation for Clinical Research, Minneapolis, Minn., April 20, 1942. Preliminary reports of part of these data may be found in: Albright, F.; Reifenstein, E. C., Jr.; and Forbes, A. P.: Conferences on the Metabolic Aspects of Convalescence (Including Bone and Wound Healing), Transactions of the First Meeting, Sept. 11-12, 1942, pages 5-7, 37-38; Transactions of the Second Meeting, December 11-12, 1942, pages 69, 96-98; Transactions of the Third Meeting, March 12-13, 1943, pages 63-65; and Transactions of the Fourth Meeting, June 11-12, 1943, pages 77-85. Transactions distributed by the Josiah Macy, Jr. Foundation, New York, N. Y.

3

The work described in this paper was done in part under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the Massachusetts General Hospital.

Find articles by Reifenstein, E. in: PubMed | Google Scholar

Medical Service of the Massachusetts General Hospital and the Department of Medicine of the Harvard Medical School, Boston

1

The expense of these studies was defrayed by grants from the Josiah Macy, Jr. Foundation, from the Rockefeller Foundation, and from the National Research Council (Committee for Research in the Problems of Sex). A bed supported by the Mallinckrodt Chemical Company on the Metabolic Ward was used for part of these studies.

2

Presented in part at the twenty-sixth annual meeting of the Association for the Study of Internal Secretions, Atlantic City, New Jersey, June 8, 1942, in connection with a symposium on “Relation of Endocrines to Skeletal Development”; an outline of this presentation may be found in: Reifenstein, E. C., Jr.; Albright, F.; Parson, W.; and Bloomberg, E.: The effect of estradiol benzoate and of testosterone propionate and of combinations of both on post-menopausal osteoporosis and senile osteoporosis, Endocrinology, 30: S1024 (1942). Also presented in part at the first annual meeting of the American Federation for Clinical Research, Minneapolis, Minn., April 20, 1942. Preliminary reports of part of these data may be found in: Albright, F.; Reifenstein, E. C., Jr.; and Forbes, A. P.: Conferences on the Metabolic Aspects of Convalescence (Including Bone and Wound Healing), Transactions of the First Meeting, Sept. 11-12, 1942, pages 5-7, 37-38; Transactions of the Second Meeting, December 11-12, 1942, pages 69, 96-98; Transactions of the Third Meeting, March 12-13, 1943, pages 63-65; and Transactions of the Fourth Meeting, June 11-12, 1943, pages 77-85. Transactions distributed by the Josiah Macy, Jr. Foundation, New York, N. Y.

3

The work described in this paper was done in part under a contract, recommended by the Committee on Medical Research, between the Office of Scientific Research and Development and the Massachusetts General Hospital.

Find articles by Albright, F. in: PubMed | Google Scholar

Published January 1, 1947 - More info

Published in Volume 26, Issue 1 on January 1, 1947
J Clin Invest. 1947;26(1):24–56. https://doi.org/10.1172/JCI101787.
© 1947 The American Society for Clinical Investigation
Published January 1, 1947 - Version history
View PDF
Browse pages

Click on an image below to see the page. View PDF of the complete article

icon of scanned page 24
page 24
icon of scanned page 25
page 25
icon of scanned page 26
page 26
icon of scanned page 27
page 27
icon of scanned page 28
page 28
icon of scanned page 29
page 29
icon of scanned page 30
page 30
icon of scanned page 31
page 31
icon of scanned page 32
page 32
icon of scanned page 33
page 33
icon of scanned page 34
page 34
icon of scanned page 35
page 35
icon of scanned page 36
page 36
icon of scanned page 37
page 37
icon of scanned page 38
page 38
icon of scanned page 39
page 39
icon of scanned page 40
page 40
icon of scanned page 41
page 41
icon of scanned page 42
page 42
icon of scanned page 43
page 43
icon of scanned page 44
page 44
icon of scanned page 45
page 45
icon of scanned page 46
page 46
icon of scanned page 47
page 47
icon of scanned page 48
page 48
icon of scanned page 49
page 49
icon of scanned page 50
page 50
icon of scanned page 51
page 51
icon of scanned page 52
page 52
icon of scanned page 53
page 53
icon of scanned page 54
page 54
icon of scanned page 55
page 55
icon of scanned page 56
page 56
Version history
  • Version 1 (January 1, 1947): No description

Article tools

  • View PDF
  • Download citation information
  • Send a comment
  • Terms of use
  • Standard abbreviations
  • Need help? Email the journal

Metrics

  • Article usage
  • Citations to this article

Go to

  • Top
  • Version history
Advertisement
Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts