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Research Letter

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A deep intronic mutation causes RAD50 deficiency through an unusual mechanism of distant exon activation
Kristine Bousset, Stefano Donega, Najim Ameziane, Tabea Fleischhammer, Dhanya Ramachandran, Miriam Poley-Gil, Detlev Schindler, Ingrid M. van de Laar, Franco Pagani, Thilo Dörk
Kristine Bousset, Stefano Donega, Najim Ameziane, Tabea Fleischhammer, Dhanya Ramachandran, Miriam Poley-Gil, Detlev Schindler, Ingrid M. van de Laar, Franco Pagani, Thilo Dörk
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A deep intronic mutation causes RAD50 deficiency through an unusual mechanism of distant exon activation

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Abstract

Authors

Kristine Bousset, Stefano Donega, Najim Ameziane, Tabea Fleischhammer, Dhanya Ramachandran, Miriam Poley-Gil, Detlev Schindler, Ingrid M. van de Laar, Franco Pagani, Thilo Dörk

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Therapeutic hypoxia for mitochondrial disease via enhancement of hemoglobin affinity and inhibition of HIF-2α
Hong Wang, Maria Miranda, Eizo Marutani, Paul Lichtenegger, Gregory R. Wojtkiewicz, Fumito Ichinose, Vamsi K. Mootha
Hong Wang, Maria Miranda, Eizo Marutani, Paul Lichtenegger, Gregory R. Wojtkiewicz, Fumito Ichinose, Vamsi K. Mootha
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Therapeutic hypoxia for mitochondrial disease via enhancement of hemoglobin affinity and inhibition of HIF-2α

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Abstract

Authors

Hong Wang, Maria Miranda, Eizo Marutani, Paul Lichtenegger, Gregory R. Wojtkiewicz, Fumito Ichinose, Vamsi K. Mootha

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Xylazine induces dopamine release and augments the effects of fentanyl
Joseph R. Trinko, Ethan Foscue, Edward M. Kong, Aakash Basu, Anouk M. Corstens, Summer L. Thompson, Alfred P. Kaye, Jane R. Taylor, Ralph J. DiLeone
Joseph R. Trinko, Ethan Foscue, Edward M. Kong, Aakash Basu, Anouk M. Corstens, Summer L. Thompson, Alfred P. Kaye, Jane R. Taylor, Ralph J. DiLeone
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Xylazine induces dopamine release and augments the effects of fentanyl

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Abstract

Authors

Joseph R. Trinko, Ethan Foscue, Edward M. Kong, Aakash Basu, Anouk M. Corstens, Summer L. Thompson, Alfred P. Kaye, Jane R. Taylor, Ralph J. DiLeone

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Complement-producing maternal microchimeric cells override infection susceptibility in complement-deficient murine offspring
Giang Pham, Raymond E. Diep, Lucien H. Turner, David B. Haslam, Sing Sing Way
Giang Pham, Raymond E. Diep, Lucien H. Turner, David B. Haslam, Sing Sing Way
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Complement-producing maternal microchimeric cells override infection susceptibility in complement-deficient murine offspring

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Authors

Giang Pham, Raymond E. Diep, Lucien H. Turner, David B. Haslam, Sing Sing Way

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Single-nuclei transcriptomics reveals TBX5-dependent targets in a patient with Holt-Oram syndrome
Jeffrey D. Steimle, Yi Zhao, Fansen Meng, Mikaela E. Taylor, Diwakar Turaga, Iki Adachi, Xiao Li, James F. Martin
Jeffrey D. Steimle, Yi Zhao, Fansen Meng, Mikaela E. Taylor, Diwakar Turaga, Iki Adachi, Xiao Li, James F. Martin
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Single-nuclei transcriptomics reveals TBX5-dependent targets in a patient with Holt-Oram syndrome

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Abstract

Authors

Jeffrey D. Steimle, Yi Zhao, Fansen Meng, Mikaela E. Taylor, Diwakar Turaga, Iki Adachi, Xiao Li, James F. Martin

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Accumulation of Epstein-Barr virus–induced cross-reactive immune responses is associated with multiple sclerosis
Hannes Vietzen, Laura M. Kühner, Sarah M. Berger, Philippe L. Furlano, Gabriel Bsteh, Thomas Berger, Paulus Rommer, Elisabeth Puchhammer-Stöckl
Hannes Vietzen, Laura M. Kühner, Sarah M. Berger, Philippe L. Furlano, Gabriel Bsteh, Thomas Berger, Paulus Rommer, Elisabeth Puchhammer-Stöckl
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Accumulation of Epstein-Barr virus–induced cross-reactive immune responses is associated with multiple sclerosis

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Abstract

Authors

Hannes Vietzen, Laura M. Kühner, Sarah M. Berger, Philippe L. Furlano, Gabriel Bsteh, Thomas Berger, Paulus Rommer, Elisabeth Puchhammer-Stöckl

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Leptin signaling maintains autonomic stability during severe influenza infection in mice
Andrés R. Muñoz-Rojas, Adam C. Wang, Lisa E. Pomeranz, Elizabeth L. Reizis, Heather W. Stout-Delgado, Ileana C. Miranda, Krishnan Rajagopalan, Tadiwanashe Gwatiringa, Roger R. Fan, Ahmad A. Huda, Neha Maskey, Roseline P. Olumuyide, Aryan S. Patel, Jeffrey M. Friedman, Diane Mathis, Kartik N. Rajagopalan
Andrés R. Muñoz-Rojas, Adam C. Wang, Lisa E. Pomeranz, Elizabeth L. Reizis, Heather W. Stout-Delgado, Ileana C. Miranda, Krishnan Rajagopalan, Tadiwanashe Gwatiringa, Roger R. Fan, Ahmad A. Huda, Neha Maskey, Roseline P. Olumuyide, Aryan S. Patel, Jeffrey M. Friedman, Diane Mathis, Kartik N. Rajagopalan
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Leptin signaling maintains autonomic stability during severe influenza infection in mice

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Abstract

Authors

Andrés R. Muñoz-Rojas, Adam C. Wang, Lisa E. Pomeranz, Elizabeth L. Reizis, Heather W. Stout-Delgado, Ileana C. Miranda, Krishnan Rajagopalan, Tadiwanashe Gwatiringa, Roger R. Fan, Ahmad A. Huda, Neha Maskey, Roseline P. Olumuyide, Aryan S. Patel, Jeffrey M. Friedman, Diane Mathis, Kartik N. Rajagopalan

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Frameshift mutation spectra overlap between constitutional mismatch repair deficiency tumors and Lynch syndrome tumors
Yurong Song, Ryan N. Baugher, Todd B. Young, Brandon Somerville, Yuriko Mori, Ligia A. Pinto, Kim E. Nichols, Robert H. Shoemaker
Yurong Song, Ryan N. Baugher, Todd B. Young, Brandon Somerville, Yuriko Mori, Ligia A. Pinto, Kim E. Nichols, Robert H. Shoemaker
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Frameshift mutation spectra overlap between constitutional mismatch repair deficiency tumors and Lynch syndrome tumors

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Abstract

Authors

Yurong Song, Ryan N. Baugher, Todd B. Young, Brandon Somerville, Yuriko Mori, Ligia A. Pinto, Kim E. Nichols, Robert H. Shoemaker

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Timing of antiretroviral therapy initiation affects intact HIV reservoirs following analytical treatment interruption
Maegan R. Manning, Jana Blazkova, Jesse S. Justement, Victoria Shi, Brooke D. Kennedy, M. Ali Rai, Catherine A. Seamon, Kathleen Gittens, Michael C. Sneller, Susan Moir, Tae-Wook Chun
Maegan R. Manning, Jana Blazkova, Jesse S. Justement, Victoria Shi, Brooke D. Kennedy, M. Ali Rai, Catherine A. Seamon, Kathleen Gittens, Michael C. Sneller, Susan Moir, Tae-Wook Chun
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Timing of antiretroviral therapy initiation affects intact HIV reservoirs following analytical treatment interruption

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Abstract

Authors

Maegan R. Manning, Jana Blazkova, Jesse S. Justement, Victoria Shi, Brooke D. Kennedy, M. Ali Rai, Catherine A. Seamon, Kathleen Gittens, Michael C. Sneller, Susan Moir, Tae-Wook Chun

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Neutralizing activity of anti–SARS-CoV-2 hyperimmune immunoglobulins and intravenous immunoglobulins against currently circulating SARS-CoV-2 variants
Lorenza Bellusci, Hana Golding, Surender Khurana
Lorenza Bellusci, Hana Golding, Surender Khurana
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Neutralizing activity of anti–SARS-CoV-2 hyperimmune immunoglobulins and intravenous immunoglobulins against currently circulating SARS-CoV-2 variants

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Authors

Lorenza Bellusci, Hana Golding, Surender Khurana

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