The American Society for Clinical Investigation (ASCI) honors Arul M. Chinnaiyan, MD, PhD, and Charles L. Sawyers, MD, with the 2026 ASCI/Harrington Prize for Innovation in Medicine. Drs. Chinnaiyan and Sawyers are recognized for their discoveries defining the molecular drivers of prostate cancer and pioneering precision therapies that have reshaped the diagnosis and treatment of prostate cancer worldwide. Dr. Chinnaiyan is the S.P. Hicks Endowed Professor of Pathology and Section Head, Michigan Center for Translational Pathology, at the University of Michigan, and a Howard Hughes Medical Institute (HHMI) Investigator. He was elected to the ASCI in 2006. Dr. Sawyers is the Marie-Josée and Henry R. Kravis Chair in Human Oncology and Pathogenesis and Chair, Human Oncology and Pathogenesis Program, at Memorial Sloan Kettering Cancer Center, as well as an HHMI Investigator. He was elected in 1999. ASCI Secretary-Treasurer Goutham Narla, Louis Newburgh Research Professor of Internal Medicine at the University of Michigan School of Medicine, interviewed the award recipients in June 2026.