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Gregg Semenza

Gregg Semenza is a geneticist at Johns Hopkins University School of Medicine whose research has been recognized with multiple awards for advancements in biomedical research, including the Wiley Prize, the ASCI Korsmeyer Award, the Gairdner Award, and, most recently, the Lasker Prize for Basic Medical Research. Semenza’s discovery of hypoxia-inducible factor (HIF) uncovered an essential oxygen-sensing pathway that supports cellular function in a multitude of physiological and pathological contexts. In an interview with JCI’s Editor at Large Ushma Neill, Semenza describes the early work that led to the discovery of HIF and the collaborations that influenced him along the way. He also discusses how tackling fundamental questions in biology can lead to serendipitous and important discoveries that ultimately impact our understanding of human disease.

Published November 1, 2016, by Ushma S. Neill

Conversations with Giants in Medicine

Related articles

A conversation with Gregg Semenza
Ushma S. Neill
Ushma S. Neill
Published November 1, 2016
Citation Information: J Clin Invest. 2016;126(11):4063-4064. https://doi.org/10.1172/JCI90960.
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Conversations with Giants in Medicine

A conversation with Gregg Semenza

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Authors

Ushma S. Neill

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