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Abstract
In healthy individuals, cells that lose expression of MHC class I molecules are quickly targeted for elimination by NK lymphocytes. A paradox in cancer immunology is the observation that many tumor cells often have a drastic reduction of MHC class I molecules, yet these cells are not eliminated by NK cells, as they should be. In this issue of the
Authors
Laurence Zitvogel, Guido Kroemer
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ISSN: 0021-9738 (print), 1558-8238 (online)