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Defending the cornea with antibacterial fragments of keratin
Michael Zasloff
Michael Zasloff
Published September 24, 2012
Citation Information: J Clin Invest. 2012;122(10):3471-3473. https://doi.org/10.1172/JCI65380.
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Commentary

Defending the cornea with antibacterial fragments of keratin

Abstract

In addition to its role in refraction, the cornea forms a barrier between the eye and environmental and infectious insults. Corneal infections are surprisingly rare, suggesting that multiple aspects of the immune system are at play in mediating protection. In this issue of the JCI, Tam et al. describe the unexpected role of a structural protein, cytokeratin 6A, in this process.

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Michael Zasloff

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