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Citation Information: J Clin Invest. 1972;51(6):1388-1397. https://doi.org/10.1172/JCI106934.
Fetal bile salt metabolism: II. Hepatic excretion of endogenous bile salt and of a taurocholate load
Abstract
Bile salt metabolism was studied in fetal dogs 1 wk before term. The size and distribution of the fetal bile salt pool were measured, and individual bile salts were identified. The hepatic excretion of endogenous bile salts was studied in bile fistula fetuses, and the capacity of this excretory mechanism was investigated by the i.v. infusion of a load of sodium taurocholate-14C up to 20 times the endogenous pool size.
Authors
R. A. Smallwood, R. Lester, G. J. Piasecki, P. D. Klein, R. Greco, B. T. Jackson
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