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Citation Information: J Clin Invest. 1969;48(10):1820-1831. https://doi.org/10.1172/JCI106148.
Abstract
The sera and red cells of three patients with severe liver disease and “spur cells” were studied. In each case the per cent of serum cholesterol which was free (unesterified) was elevated, and the serum lecithin: cholesterol acyltransferase activity was depressed. Lipoproteins with beta mobility were increased, but exhibited immune reactivity with antisera to both alpha- and beta-lipoproteins. Serum bile salt concentrations were markedly elevated and consisted primarily of chenodeoxycholic acid, with small amounts of lithocholic acid present as well.
Authors
R. A. Cooper
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