First published August 1, 2013 - More info
BM mesenchymal stromal cells (BM-MSCs) support multiple myeloma (MM) cell growth, but little is known about the putative mechanisms by which the BM microenvironment plays an oncogenic role in this disease. Cell-cell communication is mediated by exosomes. In this study, we showed that MM BM-MSCs release exosomes that are transferred to MM cells, thereby resulting in modulation of tumor growth in vivo. Exosomal
Aldo M. Roccaro, Antonio Sacco, Patricia Maiso, Abdel Kareem Azab, Yu-Tzu Tai, Michaela Reagan, Feda Azab, Ludmila M. Flores, Federico Campigotto, Edie Weller, Kenneth C. Anderson, David T. Scadden, Irene M. Ghobrial
Original citation: J. Clin. Invest. 2013;123(4):1542–1240. doi:10.1172/JCI66517.
Citation for this erratum: J. Clin. Invest. 2013;123(8):3635. doi:10.1172/JCI71663.
The bottom panel of Figure 5A was labeled incorrectly. The correct panel is below.
The JCI regrets the error.