Ionizing radiation (IR) and germline mutations in the retinoblastoma tumor suppressor gene (
Maya Kansara, Huei San Leong, Dan Mei Lin, Sophie Popkiss, Puiyi Pang, Dale W. Garsed, Carl R. Walkley, Carleen Cullinane, Jason Ellul, Nicole M. Haynes, Rod Hicks, Marieke L. Kuijjer, Anne-Marie Cleton-Jansen, Philip W. Hinds, Mark J. Smyth, David M. Thomas
A model for the roles of RB1, IL-6, and NKT cells in the senescent tumor suppressor response to IR, and their deregulation in osteosarcoma.