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Usage Information

STALing B cell responses with CD22
Craig P. Chappell, Edward A. Clark
Craig P. Chappell, Edward A. Clark
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Commentary

STALing B cell responses with CD22

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Abstract

Suppressing unwanted humoral immune responses without compromising the host’s ability to respond to foreign pathogens is a primary goal for therapies aimed at ameliorating harmful autoantibody production. Global suppression of the immune system via lymphocyte depletion and/or immunosuppressive drugs can have off-target effects, a limitation to conventional therapies. In this issue of the JCI, Macauley and colleagues utilize a novel platform to inhibit antigen-specific antibody production that preserves the immune system’s ability to respond to unrelated antigens.

Authors

Craig P. Chappell, Edward A. Clark

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Usage data is cumulative from February 2025 through February 2026.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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