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Usage Information

Sox9 and programming of liver and pancreatic progenitors
Yoshiya Kawaguchi
Yoshiya Kawaguchi
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Review Series

Sox9 and programming of liver and pancreatic progenitors

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Abstract

Recent advances in developmental biology have greatly expanded our understanding of progenitor cell programming and the fundamental roles that Sox9 plays in liver and pancreas organogenesis. In the last 2 years, several studies have dissected the behavior of the Sox9+ duct cells in adult organs, but conflicting results have left unanswered the long-standing question of whether physiologically functioning progenitors exist in adult liver and pancreas. On the other hand, increasing evidence suggests that duct cells function as progenitors in the tissue restoration process after injury, during which embryonic programs are sometimes reactivated. This article discusses the role of Sox9 in programming liver and pancreatic progenitors as well as controversies in the field.

Authors

Yoshiya Kawaguchi

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Usage data is cumulative from December 2024 through December 2025.

Usage JCI PMC
Text version 822 115
PDF 110 15
Figure 236 4
Citation downloads 112 0
Totals 1,280 134
Total Views 1,414
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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