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Citations to this article

Taking a bite: endocytosis in the maintenance of the slit diaphragm
Rosemary V. Sampogna, Qais Al-Awqati
Rosemary V. Sampogna, Qais Al-Awqati
Published November 26, 2012
Citation Information: J Clin Invest. 2012;122(12):4330-4333. https://doi.org/10.1172/JCI65785.
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Commentary

Taking a bite: endocytosis in the maintenance of the slit diaphragm

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Abstract

In the kidney, the slit diaphragm joins adjacent podocytes, forming an epithelial barrier that filters plasma into the urinary space, yet retains blood cells and proteins within the circulation. In this issue of the JCI, Soda et al. have identified clathrin-mediated endocytosis as a central mechanism by which the function and structural integrity of the slit diaphragm are maintained.

Authors

Rosemary V. Sampogna, Qais Al-Awqati

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