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Usage Information

Memory CD4+ T cells: beyond “helper” functions
Kobporn Boonnak, Kanta Subbarao
Kobporn Boonnak, Kanta Subbarao
Published July 23, 2012
Citation Information: J Clin Invest. 2012;122(8):2768-2770. https://doi.org/10.1172/JCI65208.
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Commentary

Memory CD4+ T cells: beyond “helper” functions

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Abstract

In influenza virus infection, antibodies, memory CD8+ T cells, and CD4+ T cells have all been shown to mediate immune protection, but how they operate and interact with one another to mediate efficient immune responses against virus infection is not well understood. In this issue of the JCI, McKinstry et al. have identified unique functions of memory CD4+ T cells beyond providing “help” for B cell and CD8+ T cell responses during influenza virus infection.

Authors

Kobporn Boonnak, Kanta Subbarao

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