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Usage Information

Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Derek J. Hausenloy, Derek M. Yellon
Derek J. Hausenloy, Derek M. Yellon
Published January 2, 2013
Citation Information: J Clin Invest. 2013;123(1):92-100. https://doi.org/10.1172/JCI62874.
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Review Series

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

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Abstract

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and limiting MI size is timely and effective myocardial reperfusion using either thombolytic therapy or primary percutaneous coronary intervention (PPCI). However, the process of reperfusion can itself induce cardiomyocyte death, known as myocardial reperfusion injury, for which there is still no effective therapy. A number of new therapeutic strategies currently under investigation for preventing myocardial reperfusion injury have the potential to improve clinical outcomes in patients with acute MI treated with PPCI.

Authors

Derek J. Hausenloy, Derek M. Yellon

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Usage data is cumulative from May 2024 through May 2025.

Usage JCI PMC
Text version 7,669 1,609
PDF 532 347
Figure 767 24
Table 199 0
Citation downloads 157 0
Totals 9,324 1,980
Total Views 11,304
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

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