Preventing sexually transmitted infections: back to basics
Anne Rompalo
Anne Rompalo
Published December 1, 2011
Citation Information: J Clin Invest. 2011;121(12):4580-4583. https://doi.org/10.1172/JCI61592.
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Review Series

Preventing sexually transmitted infections: back to basics

Abstract

Sexually transmitted infections (STIs) have plagued humans for millennia and can result in chronic disease, pregnancy complications, infertility, and even death. Recent technological advances have led to a better understanding of the causative agents for these infections as well as aspects of their pathogenesis that might represent novel therapeutic targets. The articles in this Review Series provide excellent updates on the recent advances in understanding of the pathogenesis of some very important and persistent STIs and discuss the importance of considering each pathogen in the broader context of the environment of the individual who it infects.

Authors

Anne Rompalo

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Figure 1

Global estimates of prevalent cases of STIs in 2005.

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Global estimates of prevalent cases of STIs in 2005. At any point in 200...
At any point in 2005, there were approximately 318 million prevalent cases of curable STIs (syphilis, gonorrhea, chlamydia, and trichomonas) and 536 million estimated HSV-2 infections (based on data from ref. 35).