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Usage Information

Erythropoietin: when liability becomes asset in neurovascular repair
Maria B. Grant, Michael E. Boulton, Alexander V. Ljubimov
Maria B. Grant, Michael E. Boulton, Alexander V. Ljubimov
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Commentary

Erythropoietin: when liability becomes asset in neurovascular repair

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Abstract

Erythropoietin (Epo) leads to the proliferation and differentiation of erythroid precursors, but is also involved in diverse nonhematopoietic biological functions. In this issue of the JCI, Chen, Smith, and colleagues demonstrate that the temporal expression of Epo is critical for determining whether physiological or pathological repair occurs following neurovascular retinal injury in the oxygen-induced retinopathy neonatal mouse model (see the related article beginning on page 526). The pleiotrophic properties of Epo make it a likely novel therapy for treatment of neurovascular damage, but the timing of its use must be carefully considered to prevent untoward effects.

Authors

Maria B. Grant, Michael E. Boulton, Alexander V. Ljubimov

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Usage data is cumulative from October 2025 through October 2026.

Usage JCI PMC
Text version 516 15
PDF 316 11
Figure 337 0
Citation downloads 311 0
Totals 1,480 26
Total Views 1,506
(Click and drag on plot area to zoom in. Click legend items above to toggle)

Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

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ISSN: 0021-9738 (print), 1558-8238 (online)

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