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Usage Information

Linkage disequilibrium maps and association mapping
Newton E. Morton
Newton E. Morton
Published June 1, 2005
Citation Information: J Clin Invest. 2005;115(6):1425-1430. https://doi.org/10.1172/JCI25032.
View: Text | PDF
Review Series

Linkage disequilibrium maps and association mapping

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Abstract

The causal chain between a gene and its effect on disease susceptibility cannot be understood until the effect has been localized in the DNA sequence. Recently, polymorphisms incorporated in the HapMap Project have made linkage disequilibrium (LD) the most powerful tool for localization. The genetics of LD, the maps and databases that it provides, and their use for association mapping, as well as alternative methods for gene localization, are briefly described.

Authors

Newton E. Morton

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Usage data is cumulative from August 2024 through August 2025.

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PDF 163 16
Figure 115 3
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Citation downloads 102 0
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Total Views 1,300
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