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Usage Information

Quantifying cerebral blood flow: regional regulation with global implications
Scott A. Small
Scott A. Small
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Retrospectives

Quantifying cerebral blood flow: regional regulation with global implications

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Abstract

In 1948, Seymour S. Kety and Carl F. Schmidt published back-to-back papers in the JCI that are widely acknowledged as landmarks. Upon publication, the studies resolved a century-old debate, irrefutably demonstrating that cerebral blood flow is regionally regulated. The reported findings turned out to be so powerful in their implications that they provided the inspirational spark that illuminated a brand-new field: functional brain imaging. Thus these papers are landmarks of the rarest kind, not only ending a controversy, but also giving birth to one of the most exciting fields within modern day neuroscience.

Authors

Scott A. Small

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Usage data is cumulative from September 2025 through September 2026.

Usage JCI PMC
Text version 547 42
PDF 257 5
Figure 435 3
Citation downloads 229 0
Totals 1,468 50
Total Views 1,518
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ISSN: 0021-9738 (print), 1558-8238 (online)

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