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New insights into atopic dermatitis
Donald Y.M. Leung, … , Ichiro Nomura, Qutayba A. Hamid
Donald Y.M. Leung, … , Ichiro Nomura, Qutayba A. Hamid
Published March 1, 2004
Citation Information: J Clin Invest. 2004;113(5):651-657. https://doi.org/10.1172/JCI21060.
View: Text | PDF | Erratum
Science in Medicine

New insights into atopic dermatitis

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Abstract

Atopic dermatitis is a chronic inflammatory skin disease associated with cutaneous hyperreactivity to environmental triggers and is often the first step in the atopic march that results in asthma and allergic rhinitis. The clinical phenotype that characterizes atopic dermatitis is the product of interactions between susceptibility genes, the environment, defective skin barrier function, and immunologic responses. This review summarizes recent progress in our understanding of the pathophysiology of atopic dermatitis and the implications for new management strategies.

Authors

Donald Y.M. Leung, Mark Boguniewicz, Michael D. Howell, Ichiro Nomura, Qutayba A. Hamid

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Important concepts in the pathobiology of AD

Important concepts in the pathobiology of AD


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