AKBI mice have improved survival following I/R injury. AKBI or WT littermates
either (A) received a lethal dose of LPS (4 μg/g body
weight, i.v.) or (B) underwent partial lobar liver I/R. Survival
was assessed for 14 days. Only times of survival are given for which deaths
occurred. No deaths occurred past the plotted times. Survival curves were
significantly different between AKBI and WT mice (P
< 0.05) as assessed using the log-rank test.