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IκBα and IκBβpossess injury context–specific functions that uniquely influence hepatic NF-κB induction and inflammation
Chenguang Fan, … , Weihong Zhou, John F. Engelhardt
Chenguang Fan, … , Weihong Zhou, John F. Engelhardt
Published February 1, 2005
Citation Information: J Clin Invest. 2005;115(2):477-477. https://doi.org/10.1172/JCI17337E1.
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IκBα and IκBβpossess injury context–specific functions that uniquely influence hepatic NF-κB induction and inflammation

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Abstract

Authors

Chenguang Fan, Qiang Li, Yulong Zhang, Xiaoming Liu, Meihui Luo, Duane Abbott, Weihong Zhou, John F. Engelhardt

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Figure 5

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AKBI mice have improved survival following I/R injury. AKBI or WT litter...
AKBI mice have improved survival following I/R injury. AKBI or WT littermates either (A) received a lethal dose of LPS (4 μg/g body weight, i.v.) or (B) underwent partial lobar liver I/R. Survival was assessed for 14 days. Only times of survival are given for which deaths occurred. No deaths occurred past the plotted times. Survival curves were significantly different between AKBI and WT mice (P < 0.05) as assessed using the log-rank test.

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