Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Wouter J. de Jonge, … , Marinus C. Lamers, Wouter H. Lamers
Published November 15, 2002
Citation Information: J Clin Invest. 2002;110(10):1539-1548. https://doi.org/10.1172/JCI16143.
View: Text | PDF
Article Aging

Arginine deficiency affects early B cell maturation and lymphoid organ development in transgenic mice

  • Text
  • PDF
Abstract

Research Article

Authors

Wouter J. de Jonge, Karin L. Kwikkers, Anje A. te Velde, Sander J.H. van Deventer, Martijn A. Nolte, Reina E. Mebius, Jan M. Ruijter, Marinus C. Lamers, Wouter H. Lamers

×

Figure 8

Options: View larger image (or click on image) Download as PowerPoint
Flow cytometric analysis of bone marrow B-lineage cells of 3-week-old wi...
Flow cytometric analysis of bone marrow B-lineage cells of 3-week-old wild-type, F/A-2+/– and F/A-2+/+ mice. B220-positive, CD43-positive lymphocytes contained within the black windows of the upper panels were analyzed for the expression of BP-1 and CD24 (lower panels). The relative size of the indicated subpopulations in the lower panels is shown as a fraction of cells in the B-lineage cell window that is shown in the upper panels. The small square schematically shows the analyzed subpopulations: A, pre-pro-B cells; B, early pro–B cells; C, late pro–B cells.

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts