Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Alerts
  • Advertising
  • Job board
  • Subscribe
  • Contact
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Author's Takes
  • Reviews
    • View all reviews ...
    • Aging (Upcoming)
    • Next-Generation Sequencing in Medicine (Jun 2022)
    • New Therapeutic Targets in Cardiovascular Diseases (Mar 2022)
    • Immunometabolism (Jan 2022)
    • Circadian Rhythm (Oct 2021)
    • Gut-Brain Axis (Jul 2021)
    • Tumor Microenvironment (Mar 2021)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Commentaries
    • Concise Communication
    • Editorials
    • Viewpoint
    • Top read articles
  • Clinical Medicine
  • JCI This Month
    • Current issue
    • Past issues

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Author's Takes
  • In-Press Preview
  • Commentaries
  • Concise Communication
  • Editorials
  • Viewpoint
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Alerts
  • Advertising
  • Job board
  • Subscribe
  • Contact
Influenza vaccines: present and future
Peter Palese, Adolfo García-Sastre
Peter Palese, Adolfo García-Sastre
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):9-13. https://doi.org/10.1172/JCI15999.
View: Text | PDF
Perspective

Influenza vaccines: present and future

  • Text
  • PDF
Abstract

Perspective

Authors

Peter Palese, Adolfo García-Sastre

×

Figure 1

Options: View larger image (or click on image) Download as PowerPoint
Epidemiology of human influenza A and B viruses. Three different influen...
Epidemiology of human influenza A and B viruses. Three different influenza A virus hemagglutinin subtypes (H1, H2, and H3) and two neuraminidase subtypes (N1 and N2) have been identified in humans over the last century. Although no live 1918 virus (solid square) is available, viral RNAs have been sequenced following RT-PCR from formalin-fixed or frozen tissue samples of 1918 victims (35). Rescue of virus containing reconstructed 1918 genes allows study of virulence characteristics of this long-gone strain (36).

Copyright © 2022 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts