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  • Volume 110, Issue 1
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/articles/view/119953
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):1-1. https://doi.org/10.1172/JCI119953.
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In This Issue

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Spotlight
The therapeutic potential of modulating the ceramide/sphingomyelin pathway
Richard Kolesnick
Richard Kolesnick
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):3-8. https://doi.org/10.1172/JCI16127.
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Perspectives
Influenza vaccines: present and future
Peter Palese, Adolfo García-Sastre
Peter Palese, Adolfo García-Sastre
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):9-13. https://doi.org/10.1172/JCI15999.
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Influenza vaccines: present and future

Abstract

Perspective

Authors

Peter Palese, Adolfo García-Sastre

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Strategies for an HIV vaccine
Norman L. Letvin
Norman L. Letvin
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):15-27. https://doi.org/10.1172/JCI15985.
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Strategies for an HIV vaccine

Abstract

Perspective

Authors

Norman L. Letvin

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Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics
Brian R. Murphy, Peter L. Collins
Brian R. Murphy, Peter L. Collins
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):21-27. https://doi.org/10.1172/JCI16077.
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Commentaries
Human CYP7A1 deficiency: progress and enigmas
Anne Beigneux, … , Alan F. Hofmann, Stephen G. Young
Anne Beigneux, … , Alan F. Hofmann, Stephen G. Young
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):29-31. https://doi.org/10.1172/JCI16076.
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Human CYP7A1 deficiency: progress and enigmas

Abstract

Commentary

Authors

Anne Beigneux, Alan F. Hofmann, Stephen G. Young

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The choreography of cyclooxygenases in the kidney
G.A. FitzGerald
G.A. FitzGerald
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):33-34. https://doi.org/10.1172/JCI16044.
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The choreography of cyclooxygenases in the kidney

Abstract

Commentary

Authors

G.A. FitzGerald

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Research Articles
Increased ABCA1 activity protects against atherosclerosis
Roshni R. Singaraja, … , Bart Staels, Michael R. Hayden
Roshni R. Singaraja, … , Bart Staels, Michael R. Hayden
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):35-42. https://doi.org/10.1172/JCI15748.
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Increased ABCA1 activity protects against atherosclerosis

Abstract

Research Article

Authors

Roshni R. Singaraja, Catherine Fievet, Graciela Castro, Erick R. James, Nathalie Hennuyer, Susanne M. Clee, Nagat Bissada, Jonathan C. Choy, Jean-Charles Fruchart, Bruce M. McManus, Bart Staels, Michael R. Hayden

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Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons
Hiroshi Yamamoto, … , Daniel J. Drucker, Joel K. Elmquist
Hiroshi Yamamoto, … , Daniel J. Drucker, Joel K. Elmquist
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):43-52. https://doi.org/10.1172/JCI15595.
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Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

Abstract

Research Article

Authors

Hiroshi Yamamoto, Charlotte E. Lee, Jacob N. Marcus, Todd D. Williams, J. Michael Overton, Marisol E. Lopez, Anthony N. Hollenberg, Laurie Baggio, Clifford B. Saper, Daniel J. Drucker, Joel K. Elmquist

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Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome
Yasushi Hanakawa, … , Masayuki Amagai, John R. Stanley
Yasushi Hanakawa, … , Masayuki Amagai, John R. Stanley
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):53-60. https://doi.org/10.1172/JCI15766.
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Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome

Abstract

Research Article

Authors

Yasushi Hanakawa, Norman M. Schechter, Chenyan Lin, Luis Garza, Hong Li, Takayuki Yamaguchi, Yasuyuki Fudaba, Koji Nishifuji, Motoyuki Sugai, Masayuki Amagai, John R. Stanley

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Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II
Zhonghua Qi, … , Jason D. Morrow, Matthew D. Breyer
Zhonghua Qi, … , Jason D. Morrow, Matthew D. Breyer
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):61-69. https://doi.org/10.1172/JCI14752.
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Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Abstract

Research Article

Authors

Zhonghua Qi, Chuan-Ming Hao, Robert I. Langenbach, Richard M. Breyer, Reyadh Redha, Jason D. Morrow, Matthew D. Breyer

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Immune complex–mediated antigen presentation induces tumor immunity
Khadija Rafiq, … , Amy Bergtold, Raphael Clynes
Khadija Rafiq, … , Amy Bergtold, Raphael Clynes
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):71-79. https://doi.org/10.1172/JCI15640.
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Immune complex–mediated antigen presentation induces tumor immunity

Abstract

Research Article

Authors

Khadija Rafiq, Amy Bergtold, Raphael Clynes

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Multiantigen/multiepitope–directed immune-specific suppression of “complex autoimmune encephalomyelitis” by a novel protein product of a synthetic gene
Ming-Chao Zhong, … , Nicole Kerlero de Rosbo, Avraham Ben-Nun
Ming-Chao Zhong, … , Nicole Kerlero de Rosbo, Avraham Ben-Nun
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):81-90. https://doi.org/10.1172/JCI15692.
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G1 and G2 cell-cycle arrest following microtubule depolymerization in human breast cancer cells
April L. Blajeski, … , Timothy J. Kottke, Scott H. Kaufmann
April L. Blajeski, … , Timothy J. Kottke, Scott H. Kaufmann
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):91-99. https://doi.org/10.1172/JCI13275.
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G1 and G2 cell-cycle arrest following microtubule depolymerization in human breast cancer cells

Abstract

Research Article

Authors

April L. Blajeski, Vy A. Phan, Timothy J. Kottke, Scott H. Kaufmann

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Increased C5a receptor expression in sepsis
Niels C. Riedemann, … , Firas S. Zetoune, Peter A. Ward
Niels C. Riedemann, … , Firas S. Zetoune, Peter A. Ward
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):101-108. https://doi.org/10.1172/JCI15409.
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Increased C5a receptor expression in sepsis

Abstract

Research Article

Authors

Niels C. Riedemann, Ren-Feng Guo, Thomas A. Neff, Ines J. Laudes, Katie A. Keller, Vidya J. Sarma, Maciej M. Markiewski, Dimitrios Mastellos, Christoph W. Strey, Carl L. Pierson, John D. Lambris, Firas S. Zetoune, Peter A. Ward

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Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype
Clive R. Pullinger, … , Mary J. Malloy, John P. Kane
Clive R. Pullinger, … , Mary J. Malloy, John P. Kane
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):109-117. https://doi.org/10.1172/JCI15387.
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Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype

Abstract

Research Article

Authors

Clive R. Pullinger, Celeste Eng, Gerald Salen, Sarah Shefer, Ashok K. Batta, Sandra K. Erickson, Andrea Verhagen, Christopher R. Rivera, Sean J. Mulvihill, Mary J. Malloy, John P. Kane

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A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes
Tania Nikolcheva, … , Carol Clayberger, Alan M. Krensky
Tania Nikolcheva, … , Carol Clayberger, Alan M. Krensky
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):119-126. https://doi.org/10.1172/JCI15336.
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A translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytes

Abstract

Research Article

Authors

Tania Nikolcheva, Stephane Pyronnet, Szu-yi Chou, Nahum Sonenberg, An Song, Carol Clayberger, Alan M. Krensky

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Heparin’s anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
Lianchun Wang, … , Ajit Varki, Jeffrey D. Esko
Lianchun Wang, … , Ajit Varki, Jeffrey D. Esko
Published July 1, 2002
Citation Information: J Clin Invest. 2002;110(1):127-136. https://doi.org/10.1172/JCI14996.
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Heparin’s anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins

Abstract

Research Article

Authors

Lianchun Wang, Jillian R. Brown, Ajit Varki, Jeffrey D. Esko

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