Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway
Jennifer L. Gommerman, … , Pauline Martin, Jeffrey L. Browning
Jennifer L. Gommerman, … , Pauline Martin, Jeffrey L. Browning
Published November 1, 2002
Citation Information: J Clin Invest. 2002;110(9):1359-1369. https://doi.org/10.1172/JCI15975.
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Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway

Abstract

Research Article

Authors

Jennifer L. Gommerman, Fabienne Mackay, Elina Donskoy, Werner Meier, Pauline Martin, Jeffrey L. Browning

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Figure 1

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FDC networks in the spleen are eliminated in animals treated with LTβR-I...
FDC networks in the spleen are eliminated in animals treated with LTβR-Ig. Representative spleens from untreated (a and b), treated (8 mg/kg LTβR-Ig) (c and d), and recovery animals (8 mg/kg treatment followed by 3-month recovery) (e and f) were stained with anti-CD35 Ab’s and developed with AP-red. Spleens were counterstained with Giemsa and photographed at ×25 (a, c, e) or ×100 (b, d, f).