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Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway
Jennifer L. Gommerman, … , Pauline Martin, Jeffrey L. Browning
Jennifer L. Gommerman, … , Pauline Martin, Jeffrey L. Browning
Published November 1, 2002
Citation Information: J Clin Invest. 2002;110(9):1359-1369. https://doi.org/10.1172/JCI15975.
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Article Aging

Manipulation of lymphoid microenvironments in nonhuman primates by an inhibitor of the lymphotoxin pathway

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Abstract

Research Article

Authors

Jennifer L. Gommerman, Fabienne Mackay, Elina Donskoy, Werner Meier, Pauline Martin, Jeffrey L. Browning

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Figure 1

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FDC networks in the spleen are eliminated in animals treated with LTβR-I...
FDC networks in the spleen are eliminated in animals treated with LTβR-Ig. Representative spleens from untreated (a and b), treated (8 mg/kg LTβR-Ig) (c and d), and recovery animals (8 mg/kg treatment followed by 3-month recovery) (e and f) were stained with anti-CD35 Ab’s and developed with AP-red. Spleens were counterstained with Giemsa and photographed at ×25 (a, c, e) or ×100 (b, d, f).

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