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TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity
Ganesan Ramesh, W. Brian Reeves
Ganesan Ramesh, W. Brian Reeves
Published September 15, 2002
Citation Information: J Clin Invest. 2002;110(6):835-842. https://doi.org/10.1172/JCI15606.
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Article Inflammation

TNF-α mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity

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Abstract

Research Article

Authors

Ganesan Ramesh, W. Brian Reeves

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Figure 4

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Effects of TNF-α inhibitors on cytokine gene expression. Cytokine gene e...
Effects of TNF-α inhibitors on cytokine gene expression. Cytokine gene expression was measured 72 hours after injection of cisplatin (black bars) or cisplatin and either GM6001 (white bars) or pentoxifylline (gray bars) by either RPA or real-time RT-PCR. In each experiment, the expression levels were normalized to the expression of either GAPDH or actin and are expressed relative to saline-treated control mice. n = 3–5 for each condition.

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