Intensive recruitment of CCR4-bearing T cells by MDC. The effect of MDC on the recruitment of CCR4-bearing CD4⁺ T cells and APCs to the pancreas was analyzed in MDC-TG (black bars, n = 3) and non-TG NOD mice (white bars, n = 3) by FACS. (a) Percentage and (b) absolute cell number of pancreas-infiltrating CCR4⁺CD4⁺ T cells. (c) Absolute number of CCR4⁺CD8⁺ T cells and APCs that infiltrated pancreas. Data shown are representative of three separate experiments.