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Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23
Edwin Liu, … , Fred D. Finkelman, George S. Eisenbarth
Edwin Liu, … , Fred D. Finkelman, George S. Eisenbarth
Published October 1, 2002
Citation Information: J Clin Invest. 2002;110(7):1021-1027. https://doi.org/10.1172/JCI15488.
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Article Immunology

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

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Abstract

Research Article

Authors

Edwin Liu, Hiroaki Moriyama, Norio Abiru, Dongmei Miao, Liping Yu, Robert M. Taylor, Fred D. Finkelman, George S. Eisenbarth

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Figure 4

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NOD mice immunized with a lower dose of B:9-23 (10 μg/dose) also develop...
NOD mice immunized with a lower dose of B:9-23 (10 μg/dose) also develop anti–B:9-23 antibodies, but in lower levels that are better detected at dilutions of 1:500.

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