JCI - Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

Edwin Liu, … , Fred D. Finkelman, George S. Eisenbarth

Published October 1, 2002
Citation Information: J Clin Invest. 2002;110(7):1021-1027. https://doi.org/10.1172/JCI15488.

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Article Immunology

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Clinical anaphylaxis score of NOD mice sensitized and induced to experience anaphylaxis with B:9-23 peptide. Mice were pretreated with control antibodies, EM95, 2.4G2, or both EM95 and 2.4G2.

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23

Abstract

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