Collagen-binding integrin α1β1 regulates intestinal inflammation in experimental colitis
Christian F. Krieglstein, Wolfgang H. Cerwinka, Andrew G. Sprague, F. Stephen Laroux, Matthew B. Grisham, Victor E. Koteliansky, Norbert Senninger, D. Neil Granger, Antonin R. de Fougerolles
Christian F. Krieglstein, Wolfgang H. Cerwinka, Andrew G. Sprague, F. Stephen Laroux, Matthew B. Grisham, Victor E. Koteliansky, Norbert Senninger, D. Neil Granger, Antonin R. de Fougerolles
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Article Immunology

Collagen-binding integrin α1β1 regulates intestinal inflammation in experimental colitis

Abstract

Research Article

Authors

Christian F. Krieglstein, Wolfgang H. Cerwinka, Andrew G. Sprague, F. Stephen Laroux, Matthew B. Grisham, Victor E. Koteliansky, Norbert Senninger, D. Neil Granger, Antonin R. de Fougerolles

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Figure 4

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α1-deficient mice showed decreased leukocyte infiltration and were prote...
α1-deficient mice showed decreased leukocyte infiltration and were protected from DSS-associated mucosal injury. Shown are representative photomicrographs at ×100 magnification of colonic cross sections after hematoxylin and eosin staining from WT (a) or α1-deficient mice (b) treated for 7 days with DSS. Bar represents 100 μm.