Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration
Flavio Curnis, … , Angelina Sacchi, Angelo Corti
Flavio Curnis, … , Angelina Sacchi, Angelo Corti
Published August 15, 2002
Citation Information: J Clin Invest. 2002;110(4):475-482. https://doi.org/10.1172/JCI15223.
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Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

Abstract

Research Article

Authors

Flavio Curnis, Angelina Sacchi, Angelo Corti

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Effect of melphalan, alone (a) or in combination with NGR-mTNF (c) or mT...
Effect of melphalan, alone (a) or in combination with NGR-mTNF (c) or mTNF (d), on the tumor growth (a–d) and body weight (e and f) of mice bearing B16F1 melanoma. The animals were treated intraperitoneally with the drugs and the doses indicated in each panel (five animals per group) at days 4, 7, and 9 after tumor implantation (indicated by arrows).