Gas6^–/– mice showed less renal injury than did wild-type mice. (a) Survival curves of wild-type (broken line) or Gas6^–/– (solid line) mice after injection of NTS. Each group consisted of 16 mice. (b) Urinary albumin levels of wild-type (open squares) and Gas6^–/– (filled squares) mice after injection of anti-GBM Ab on the day indicated. Each group consisted of five mice on day 0, nine mice on day 7, eight mice on day 14, and six mice on day 21. Data are expressed as mean ± SD. (c) Serum albumin levels in wild-type (open squares) and Gas6^–/– (filled squares) mice on the day indicated during the course of NTN. Each group consisted of four mice with the exception of a group of six mice on day 21. Data are expressed as mean ± SD. *P < 0.05. **P < 0.01.