Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood
Christy M. Gliniak and Philipp E. Scherer
Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Address correspondence to: Philipp E. Scherer, Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-8549, USA. Phone: 214.648.8715; Email: philipp.scherer@utsouthwestern.edu.
Find articles by
Gliniak, C.
in:
JCI
|
PubMed
|
Google Scholar
|
Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Address correspondence to: Philipp E. Scherer, Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, Texas 75390-8549, USA. Phone: 214.648.8715; Email: philipp.scherer@utsouthwestern.edu.
Find articles by
Scherer, P.
in:
JCI
|
PubMed
|
Google Scholar
|
First published May 13, 2019 - More info
J Clin Invest. 2019;129(6):2198–2200. https://doi.org/10.1172/JCI128830.
© 2019 American Society for Clinical Investigation
The study of beige adipose tissue (BeAT) has recently gained popularity because of its potential as a therapeutic target for the treatment of obesity and other metabolic disorders. While BeAT regulation is well understood in adults, the critical signals regulating BeAT during infant development need to be better defined. The bioactive components in breast milk have been primarily studied in the context of immunity. In this issue of the JCI, Yu and Dilbaz et al. identify how a class of breast milk–specific lipid mediators referred to as alkylglycerols (AKGs) maintain BeAT in infants and prevent the transdifferentiation of BeAT into lipid-storing white adipose tissue (WAT).
- Purchase this article
- $10
- Purchasing this article will give you full access for the calendar year.
- Purchase Site Pass
- $25
- This will give you access to every article on the site for 24 hours.
- Online subscription
- $95
- Individual online subscriptions give you full online access for the calendar year.
- Print subscription
- $795
- Individual print subscriptions give you the print journal and full online access for the year.
- JCI This Month subscription
- $125
- JCI This Month is a 16- to 20-page overview of the articles published each month
- Subscribing to JCI This Month also gives subscribers full online access for the calendar year.
- *Price outside U.S. and Canada: $225.
Copyright © 2019 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)