Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo
Wolfgang E. Gallwitz, Theresa A. Guise, Gregory R. Mundy
Wolfgang E. Gallwitz, Theresa A. Guise, Gregory R. Mundy
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Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo

Abstract

Research Article

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Wolfgang E. Gallwitz, Theresa A. Guise, Gregory R. Mundy

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(a) Effect of 6-thioguanine on the 1.1 kb 5′-flanking region of the PTHr...
(a) Effect of 6-thioguanine on the 1.1 kb 5′-flanking region of the PTHrP gene. (b) Effect of 6-thioguanosine on the 1.1 kb 5′-flanking region of the PTHrP gene. (c) Effect of purine on the 1.1 kb 5′-flanking region of the PTHrP gene. (d) Effect of dexamethasone on the 1.1 kb 5′-flanking region of the PTHrP gene. Values in all panels represent means ± SEM (n = 3 per group). Ctrl, control; Untr, MDA-MB-231 cells stably transfected with the 1.1 kb 5′-flanking region/luciferase reporter gene. *P < 0.05.