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Usage Information

Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis.
H G Kraft, … , W Vogel, G Utermann
H G Kraft, … , W Vogel, G Utermann
Published January 1, 1989
Citation Information: J Clin Invest. 1989;83(1):137-142. https://doi.org/10.1172/JCI113849.
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Research Article

Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis.

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Abstract

Liver transplantation provides a unique opportunity to investigate the contribution in vivo of the liver to the synthesis and degradation of genetically polymorphic plasma proteins. We have determined the genetic polymorphisms plasma proteins. We have determined the genetic polymorphisms of apo A-IV, apo E, and of the Lp(a) glycoprotein (apo (a] in the plasma of subjects undergoing liver transplantation and in respective organ donors. The results show that in humans, greater than 90% of the plasma apo E and virtually all apo (a) are liver derived, whereas this organ does not significantly contribute to plasma apo A-IV levels.

Authors

H G Kraft, H J Menzel, F Hoppichler, W Vogel, G Utermann

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Usage data is cumulative from July 2024 through July 2025.

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Text version 264 20
PDF 53 29
Figure 0 2
Scanned page 202 15
Citation downloads 63 0
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Total Views 648
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