Rat Anterior Pituitary: DISTINCTION OF AN ∼8S, CORTICOSTERONE-PREFERRING SPECIES FROM DEXAMETHASONE-BINDING GLUCOCORTICOID RECEPTORS

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Abstract

Studies on the feedback inhibition of ACTH release by steroid hormones and on the binding of tritiated steroids by the pituitary have prompted the hypothesis that receptors in addition to or other than classical glucocorticoid receptors may mediate steroid hormone effects in this tissue. Accordingly, we have asked whether more than one glucocorticoid-binding species, distinct from corticosteroid binding globulin, can be found in rat anterior pituitary gland.

Authors

Zygmunt S. Krozowski, John W. Funder