Citations to this article

Reactivity of a monoclonal antibody with human ovarian carcinoma.
R C Bast Jr, … , R B Colvin, R C Knapp
R C Bast Jr, … , R B Colvin, R C Knapp
Published November 1, 1981
Citation Information: J Clin Invest. 1981;68(5):1331-1337. https://doi.org/10.1172/JCI110380.
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Research Article

Reactivity of a monoclonal antibody with human ovarian carcinoma.

Abstract

A murine monoclonal antibody (OC125) has been developed that reacts with each of six epithelial ovarian carcinoma cell lines and with cryopreserved tumor tissue from 12 of 20 ovarian cancer patients. By contrast, the antibody does not bind to a variety of nonmalignant tissues, including adult and fetal ovary. OC125 reacts with only 1 of 14 cell lines derived from nonovarian neoplasms and has failed to react with cryostat sections from 12 nonovarian carcinomas.

Authors

R C Bast Jr, M Feeney, H Lazarus, L M Nadler, R B Colvin, R C Knapp

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