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Fat Digestion in the Newborn: CHARACTERIZATION OF LIPASE IN GASTRIC ASPIRATES OF PREMATURE AND TERM INFANTS
Margit Hamosh, John W. Scanlon, Dvora Ganot, Melodie Likel, Kathleen B. Scanlon, Paul Hamosh
Margit Hamosh, John W. Scanlon, Dvora Ganot, Melodie Likel, Kathleen B. Scanlon, Paul Hamosh
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Fat Digestion in the Newborn: CHARACTERIZATION OF LIPASE IN GASTRIC ASPIRATES OF PREMATURE AND TERM INFANTS

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Abstract

We have measured lipolytic activity in gastric aspirates obtained at birth in a group of 142 infants. The infants ranged in gestational age from 26 to 41 wk. Lipolytic activity, measured by the hydrolysis of long chain triglyceride ([tri-3H]oleate), and expressed as nanomoles FFA per milliliter gastric aspirate per minute was 333±66 in 55 small premature infants (gestational age 26-34 wk and body wt 750-2,000 g) and 558±45 in a group of 87 larger infants (gestational age 35-41 wk and body wt 2,020-4,000 g). No activity was detected in seven infants with an unusually low pH in the gastric aspirate, 2.88±0.44 (compared with a mean pH level of 5.59±0.22 in the other 135 infants).

Authors

Margit Hamosh, John W. Scanlon, Dvora Ganot, Melodie Likel, Kathleen B. Scanlon, Paul Hamosh

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