Advertisement

Research Article Free access | 10.1172/JCI110071

Neutrophil-endothelial cell interactions on endothelial monolayers grown on micropore filters.

R F Taylor, T H Price, S M Schwartz, and D C Dale

Find articles by Taylor, R. in: PubMed | Google Scholar

Find articles by Price, T. in: PubMed | Google Scholar

Find articles by Schwartz, S. in: PubMed | Google Scholar

Find articles by Dale, D. in: PubMed | Google Scholar

Published February 1, 1981 - More info

Published in Volume 67, Issue 2 on February 1, 1981
J Clin Invest. 1981;67(2):584–587. https://doi.org/10.1172/JCI110071.
© 1981 The American Society for Clinical Investigation
Published February 1, 1981 - Version history
View PDF
Abstract

We have developed a technique for growing endothelial monolayers on micropore filters. These monolayers demonstrate confluence by phase and electron microscopy and provide a functional barrier to passage of radiolabeled albumin. Neutrophils readily penetrate the monolayer in response to chemotaxin, whereas there is little movement in the absence of chemotaxin. This system offers unique advantages over available chemotaxis assays and may have wider applications in the study of endothelial function.

Images.

Browse pages

Click on an image below to see the page. View PDF of the complete article

Version history
  • Version 1 (February 1, 1981): No description
Advertisement
Advertisement