Advertisement
Research Article Free access | 10.1172/JCI109818
Find articles by Farese, R. in: JCI | PubMed | Google Scholar
Find articles by Bidot-López, P. in: JCI | PubMed | Google Scholar
Find articles by Sabir, A. in: JCI | PubMed | Google Scholar
Find articles by Smith, J. in: JCI | PubMed | Google Scholar
Find articles by Schinbeckler, B. in: JCI | PubMed | Google Scholar
Find articles by Larson, R. in: JCI | PubMed | Google Scholar
Published June 1, 1980 - More info
Parathyroid hormone(PTH) rapidly increases the concentrations of diphosphoinositide and triphosphoinositide in rabbit kidney cortex. Cycloheximide pretreatment abolishes these effects of PTH. These findings are similar to those reported for adrenocorticotropin and cyclic AMP action in the adrenal cortex, and suggest a common mechanism. Cycloheximide-sensitive effects of PTH, e.g., phosphaturia, may require polyphosphoinositides and/or other phospholipids.
Click on an image below to see the page. View PDF of the complete article