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Usage Information

Effect of Age and Magnesium Depletion on Bone Magnesium Pools in Rats
Allen C. Alfrey, … , Nancy L. Miller, Richard Trow
Allen C. Alfrey, … , Nancy L. Miller, Richard Trow
Published November 1, 1974
Citation Information: J Clin Invest. 1974;54(5):1074-1081. https://doi.org/10.1172/JCI107851.
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Research Article

Effect of Age and Magnesium Depletion on Bone Magnesium Pools in Rats

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Abstract

In vivo and in vitro studies were carried out to characterize the exchangeable bone magnesium pool and determine what effect age and magnesium depletion has on bone magnesium. A highly significant correlation was found between the size of the in vitro elutable and in vivo exchangeable bone magnesium (r=0.97). To show that the exchangeable bone magnesium was the surface-limited bone magnesium, elution studies were performed 4 h after the in vivo administration of radiomagnesium. Specific activity in the eluant was 85% of that found in the serum at time of death, suggesting that the elutable and exchangeable bone magnesium pools were largely the same pool.

Authors

Allen C. Alfrey, Nancy L. Miller, Richard Trow

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Usage data is cumulative from August 2024 through August 2025.

Usage JCI PMC
Text version 270 15
PDF 133 16
Scanned page 452 1
Citation downloads 151 0
Totals 1,006 32
Total Views 1,038
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