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Usage Information

The Amino Acid Sequence of a Major Nonimmunoglobulin Component of Some Amyloid Fibrils
Mark Levin, … , Blas Frangione, Mordechai Pras
Mark Levin, … , Blas Frangione, Mordechai Pras
Published October 1, 1972
Citation Information: J Clin Invest. 1972;51(10):2773-2776. https://doi.org/10.1172/JCI107098.
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Research Article

The Amino Acid Sequence of a Major Nonimmunoglobulin Component of Some Amyloid Fibrils

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Abstract

The complete amino acid sequence of a protein, acid soluble fraction, (ASF) which constitutes up to 50% of amyloid fibrils from a patient with familial Mediterranean fever has been obtained. Partial amino acid sequences of three other proteins from patients with secondary amyloidosis were identical in the regions studied except for an alanine-valine interchange in one. The ASF contains no cysteine, does not resemble any known immunoglobulin, and has not been detected as yet in myeloma-associated amyloid.

Authors

Mark Levin, Edward C. Franklin, Blas Frangione, Mordechai Pras

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Usage data is cumulative from June 2024 through June 2025.

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Text version 210 5
PDF 68 18
Scanned page 142 2
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