Bilirubin conjugates in bile of man and rat in the normal state and in liver disease

• Text
• PDF

Abstract

Conjugates of bilirubin were studied in normal bile of man and rat, and in bile of liver patients. In general human bile was obtained by duodenal intubation. In addition T-tube bile was examined in patients operated on for mechanical obstruction. The bile pigment compositions of duodenal and T-tube bile were similar in two patients where comparison was possible. Obstruction of the bile duct in rats was used as an animal model for obstructive jaundice.

Authors

J. Fevery, B. Van Damme, R. Michiels, J. De Groote, K. P. M. Heirwegh