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Usage Information

Studies on the purification and characterization of human factor VIII
Sally L. Marchesi, … , N. Raphael Shulman, Harvey R. Gralnick
Sally L. Marchesi, … , N. Raphael Shulman, Harvey R. Gralnick
Published August 1, 1972
Citation Information: J Clin Invest. 1972;51(8):2151-2161. https://doi.org/10.1172/JCI107022.
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Research Article

Studies on the purification and characterization of human factor VIII

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Abstract

Factor VIII (antihemophilic globulin) has been prepared from Hyland method IV AHG and cryoprecipitate using limited chymotryptic digestion followed by Sepharose gel filtration. The activity of factor VIII is unaffected by the digestion procedure, while fibrinogen in converted to large noncoagulable fragments.

Authors

Sally L. Marchesi, N. Raphael Shulman, Harvey R. Gralnick

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Usage data is cumulative from May 2024 through May 2025.

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